ÿþ<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/html4/loose.dtd"> <html> <head> <meta http-equiv="Content-Type" content="text/html; charset=iso-8859-1"> <title>SWISS BIO GRID - Bio-data Project</title> <link href="swissbiogrid_css.css" rel="stylesheet" type="text/css"> <style type="text/css"> <!-- body { background-color: #FFFFFF; } a:link { color: #000000; text-decoration: none; } a:active { color: #AD1227; text-decoration: none; } a:visited { color: #000000; text-decoration: none; } a:hover { color: #AD1227; text-decoration: none; } --> </style> </head> <body> <table width="100%" border="0" cellspacing="0" cellpadding="0"> <tr> <td align="center" valign="middle"><table width="801" border="0" cellspacing="0" cellpadding="0"> <tr> <td align="center" bgcolor="#000000"><table width="799" border="0" cellspacing="0" cellpadding="0"> <tr bgcolor="#FFFFFF"> <td><img src="graphics/black_line.gif" width="799" height="1"></td> </tr> <tr bgcolor="#FFFFFF"> <td><img src="graphics/header.gif" width="799" height="91" border="0" usemap="#Map"></td> </tr> <tr align="left" valign="top" bgcolor="#FFFFFF"> <td><img src="graphics/navitop_research.gif" width="799" height="30" border="0" usemap="#Map2"><br> <table width="200" align="left" border="0" cellpadding="0" cellspacing="0"> <tr> <td bgcolor="#000000"><span class="navi_invers">&nbsp;SwissBioGrid</span></td> </tr> <tr> <td bgcolor="#DAE0E5">&nbsp;</td> </tr> <tr> <td bgcolor="#DAE0E5"> <span class="navi">&nbsp;<a href="project_and_proof.html">Proof of Concept study</a> </span><br> </td> </tr> <tr> <td bgcolor="#DAE0E5"><img src="graphics/line.gif" width="200" height="3"></td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi"><img src="graphics/line.gif" width="200" height="3"></td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi"><span class="navi_invers">&nbsp;</span><a href="grid.html">GRID Middleware</a><br> </td> </tr> <tr> <td bgcolor="#DAE0E5"><span class="navi"><img src="graphics/line.gif" width="200" height="3"></span></td> </tr> <tr> <td bgcolor="#DAE0E5"><span class="navi">&nbsp;<a href="proteomics.html">Proteomics Project</a></span><br> </td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi"><img src="graphics/line.gif" width="200" height="3"></td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi">&nbsp;<a href="Bio-data-Project.html">Bio-data Project </a></td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi"><img src="graphics/line.gif" width="200" height="3"></td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi">&nbsp;</td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi">&nbsp;<a href="http://www.billyjoeleltonjohn.com">Billy Joel Elton John</a></td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi">&nbsp;<a href="http://www.alicecoopertickets.net">Alice Cooper Tickets</a></td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi">&nbsp;<a href="http://www.bronxtickets.org">Bronx Tickets</a></td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi">&nbsp;</td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi">&nbsp;</td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi"><img src="graphics/line.gif" width="200" height="3"></td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi">&nbsp;<span class="navi"><a href="contact.html">Contact</a></span><br> </td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi"><img src="graphics/line.gif" width="200" height="3"></td> </tr> <tr> <td bgcolor="#DAE0E5"><span class="navi">&nbsp;<a href="index-2.html">Home</a></span><br> </td> </tr> <tr> <td bgcolor="#DAE0E5"><img src="graphics/line.gif" width="200" height="3"></td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi"><a href="javascript:history.back()">&nbsp;Back</a></td> </tr> <tr> <td bgcolor="#DAE0E5" class="navi"><img src="graphics/line.gif" width="200" height="3"></td> </tr> </table> <table width="15" align="left" border="0" cellpadding="0" cellspacing="0" bgcolor="#ffffff"> <tr> <td width="15">&nbsp;</td> </tr> </table> <table width="345" border="0" align="left" cellpadding="0" cellspacing="0" bgcolor="#ffffff"> <tr> <td width="345" valign="top"><p><font face="Arial"><span class="titel"><strong>Bio-data Project </strong></span></font></p> <p align="justify" class="navi" style="margin-bottom: 0pt;"> <span class="text">The data needed for the processing on the BioGrid reside in what people call  databases'. These are just flat files of various formats that are regularly updated by the maintainers of these  databases'.<br> In order to avoid confusion for those who think of databases in the RDBMS sense of the word, in this document the term  bio-databases' will be used. In order to be able to submit jobs on the distributed infrastructure of the BioGrid, the files of the various bio-databases need to be easily accessible from every node in the BioGrid. Of course there are many factors that need to be taken into account when addressing the distributed bio-database problem in the BioGrid. </span></p> <p align="justify" class="text" style="margin-bottom: 0pt;">The points above build the basis for a possible design of a distributed bio-database infrastructure in Switzerland. There are other relevant points to consider that are not directly but indirectly influencing the design: </p> <ul> <li class="navi"> <div align="justify" class="text">Swiss users preferred. Somehow it should be possible to assure that the Swiss academic users get preferred downloads over non-Swiss or non-academic users. </div> </li> <li class="navi"> <div align="justify" class="text">Distributed Expertise. The people having the in-depth knowledge about the various bio-databases, their content, etc. are spread across all of Switzerland and beyond. </div> </li> <li class="navi"> <div align="justify" class="text">Uniform Environment. The executables making use of a database need to be able to run at any site. Therefore it is necessary that localities are collected into a uniform BioGrid environment that can be configured individually at each site while providing uniformity and  ubiquitousness' to the application. o Agreement on a set of environment variables to be used in the Grid job is necessary o The environment needs to be extensible </div> </li> <li class="navi"> <div align="justify" class="text">Distribution of applications. Not only the bio-databases but also the corresponding applications could be mirrored and made readily available to the community, if they come without licensing constraints and need to be updated regularly. </div> </li> </ul> <p align="justify" class="text" style="margin-bottom: 0pt;">These requirements should all be taken into consideration. Some mechanisms already exist to mirror bio-databases at individual institutions. </p> <hr> <p> <a href="http://www.ericclaptontickets.biz">ERIC CLAPTON TICKETS</a><br> Buy Eric Clapton tickets today so you can see this legend in concert at an amphitheatre near you. This once in a lifetime experience is always worth the wait, and worth buying the best seats. So for premium tickets, visit <a href="http://www.ericclaptontickets.biz">Eric Clapton Tickets</a>. 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