Proteomics Project

The Proteomics project is a collaboration between the SBG partners Markus Mueller's group at ETH/IMSB, and Ron Appel's Proteome Informatics Group (PIG) at the SIB in Geneva, with participation also from CSCS and Vital-IT.

The Swiss Protein Identification Toolbox (swissPIT) is a project at the Swiss Institute for Bioinformatics (SIB) in Geneva which aims at the development of an automated analysis system to identify proteins using MS and MS/MS based data. One of the major problems in proteomics is the absence of standardized workflows to analyse the data. This includes the pre-processing part as well as the final identification of peptides and proteins. The main ideas of swissPIT include not only the use of different identification tool in parallel but also the meaningful concatenation of different identification strategies at the same time.

• To make an set of proteomics tools available over the SwissBioGRID via a uniform interface (portal).
• To construct an integrated proteomics "pipeline" which will allow the tools to be used within a unified workflow environment.
• To make most effective use of the computational resources available at Vital-IT, UniZH, ETH and CSCS via the SwissBioGRID.
• To support collaboration and sharing between the various participating groups.